Stem Cells and Nanotechnology in Spinal Injury Repair: Difference between revisions

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<br><font size=3>'''Mentors:''' Chythar Skyfire, MD; Dassa Alexander, PD, PDS</font>
<br><font size=3>'''Mentors:''' Chythar Skyfire, MD; Dassa Alexander, PD, PDS</font>
<br><font size=3>'''Supervising Professor:''' Professor Talsan Rheyfli, Eng.D. </font>
<br><font size=3>'''Supervising Professor:''' Professor Talsan Rheyfli, Eng.D. </font>
<br><font size=3>'''Approved By:''' </font>
<br><font size=3>'''Approved by:'''Veezah Bijan, Eng. D., Dean of Engineering Department - Daystrom Institute </font>


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[[File:Borg-nanoprobe.jpg|left|thumb|100px|Nanotechnology schematics.]] Nanotechnology has also found applications in medicine since the early 21st century when mankind first imagined the use of nano (mini) robots to repair the body at a cellular level. One of the most progressive uses of the technology was engineered nanoparticles designed to deliver a variety of elements such as heat and drugs to specific cells, leading to direct treatment of these cells in hopes of reducing damage to healthy cells in the body and allowing for earlier detection of disease or mutations in cells. (Nanotechnology in Medicine: Nanomedicine, 2394).  
[[File:Borg-nanoprobe.jpg|left|thumb|100px|Nanotechnology schematics.]] Nanotechnology has also found applications in medicine since the early 21st century when mankind first imagined the use of nano (mini) robots to repair the body at a cellular level. One of the most progressive uses of the technology was engineered nanoparticles designed to deliver a variety of elements such as heat and drugs to specific cells, leading to direct treatment of these cells in hopes of reducing damage to healthy cells in the body and allowing for earlier detection of disease or mutations in cells. (Nanotechnology in Medicine: Nanomedicine, 2394).  


[Add more on nanotech in medicine]
Another important aspect of the field, nano-gel, injected as a liquid into the spinal column, supports stem cells in that it not only prevents scar tissue from forming as an injury site heals, it also encourages the stem cells to create new cells that produce myelin, the material that surrounds the nerves of the spinal cord and prevents them from being damaged. The gel is often used in combination with stem cell therapies to heal spinal cord injuries, including severed nerve fibers and supports the growth of axioms both up into the brain and down to the legs, bridging the connection. Patients who were previously paralyzed are able to regain some, if not all of their mobility. [https://www.sciencedaily.com/releases/2008/04/080402114819.htm| Promising New Nanotechnology For Spinal Cord Injury, 2385]


[[File:Genetronicreplicator.jpg|right|thumb|70px| Genetronic replicator designed by Dr. Russel.]]  
[[File:Genetronicreplicator.jpg|right|thumb|70px| Genetronic replicator designed by Dr. Russel.]]  
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[[File:Laelspine_postreplacementsurgery.jpg|75px|right|thumb|Lael's spine after the replacement surgery.]]  
[[File:Laelspine_postreplacementsurgery.jpg|75px|right|thumb|Lael's spine after the replacement surgery.]]  


<h3>Discussion</h3>
<h3>Discussion & Conclusions</h3>


Prior to her surgery, the patient experienced significant difficulties with mobility that, at times, impeded her ability to perform her duties. The patient also experienced chronic pain at the site of the injury and stiffening of her limbs. The continued degradation of the nanites used to keep the patient mobile meant that had she not attempted the procedure, she would have experienced near complete paralysis and would likely have been confined to a hoverchair until an alternate solution could be found. Post-surgery, the patient reports a drastic decrease in pain as well as increased mobility. The use of physical therapy techniques has helped the patient to regain much of her previous mobility and she continues to make excellent progress. The patient has reported only mild side effects from the procedure such as moderate at the surgical site, fatigue, and headaches, none of which are unexpected. The patient attends twice month appointments to monitor healing progress via deep scans and evaluate for potential signs of [https://www.laserspineinstitute.com/back_problems/fbss/| Failed Back Surgery Syndrome (FBSS)], in which the patient experiences unusual chronic pain post-surgery. Despite these risks, the patient's primary physician anticipates that she will make a full recovery.
Prior to her surgery, the patient experienced significant difficulties with mobility that, at times, impeded her ability to perform her duties. The patient also experienced chronic pain at the site of the injury and stiffening of her limbs. The continued degradation of the nanites used to keep the patient mobile meant that had she not attempted the procedure, she would have experienced near complete paralysis and would likely have been confined to a hoverchair until an alternate solution could be found. Post-surgery, the patient reports a drastic decrease in pain as well as increased mobility. The use of physical therapy techniques has helped the patient to regain much of her previous mobility and she continues to make excellent progress. The patient has reported only mild side effects from the procedure such as moderate at the surgical site, fatigue, and headaches, none of which are unexpected. The patient attends twice month appointments to monitor healing progress via deep scans and evaluate for potential signs of [https://www.laserspineinstitute.com/back_problems/fbss/| Failed Back Surgery Syndrome (FBSS)], in which the patient experiences unusual chronic pain post-surgery. Despite these risks, the patient's primary physician anticipates that she will make a full recovery.
<h3>Conclusions</h3>


<h2>References</h2>
<h2>References</h2>
*[https://www.laserspineinstitute.com/back_problems/fbss/ What Is Failed Back Surgery Syndrome (FBSS)?] - Laser Spine Institute (2394) Accessed Stardate 239405.17.
*[http://memory-beta.wikia.com/wiki/Genitronic_replication Genetronic Replication] - ''Memory Beta.'' (2394) Accessed Stardate 239405.17.
*[http://memory-beta.wikia.com/wiki/Genitronic_replication Genetronic Replication] - ''Memory Beta.'' (2394) Accessed Stardate 239405.17.
*[https://stemgenex.com/studies/multiple-sclerosis-stem-cell-studies/#tab-5. Multiple Sclerosis Stem Cell Therapy] - ''StemGenex''. (2394) Accessed Stardate 239405.17.
*[https://stemgenex.com/studies/multiple-sclerosis-stem-cell-studies/#tab-5. Multiple Sclerosis Stem Cell Therapy] - ''StemGenex''. (2394) Accessed Stardate 239405.17.
*[http://www.understandingnano.com/medicine.html. Nanotechnology in Medicine - Nanomedicine] - ''UnderstandingNano''. (2393) Accessed Stardate 239405.17.
*[https://www.sciencedaily.com/releases/2008/04/080402114819.htm Promising New Nanotechnology in Spinal Injury Repair] Science Daily (2385) Accessed Stardate 239405.17.
*[http://www.understandingnano.com/medicine.html Nanotechnology in Medicine - Nanomedicine] - ''UnderstandingNano''. (2393) Accessed Stardate 239405.17.
 
*[http://www.nationalmssociety.org/Research/Research-News-Progress/Stem-Cells-in-MS Stem Cells in MS] - ''National Multiple Sclerosis Society''. (2394) Accessed Stardate 239405.17.  
*[http://www.nationalmssociety.org/Research/Research-News-Progress/Stem-Cells-in-MS Stem Cells in MS] - ''National Multiple Sclerosis Society''. (2394) Accessed Stardate 239405.17.